Primary Synovial Cell Sarcoma of the Socket: Case Report

Abstract

We report the first case of primary synovial cell sarcoma of the socket and the seventh of the globe and orbit in literature. Synovial cell sarcomas are relatively common intermediate to high grade malignant soft tissue tumours often with an initial indolent course and may present as a masquerade syndrome as in this case where a 12 year old female initially presented with a unilateral cataract of the right eye and cataract surgery was done with a posterior capsular intraocular lens implant. The patient was seen about 5 years later with endophthalmitis and anterior staphyloma for which evisceration was done. Seven months later the patient presented yet again with a mass in the right socket. Debulking surgery was done following an incisional biopsy for histopathology which showed a biphasic synovial cell sarcoma. Bcl-2 was positive on immunohistochemistry confirming the diagnosis. The patient was treated with chemotherapy followed by radiotherapy and has been healthy with no evidence of recurrence and is on regular follow up.