COECSA, Journal, Ophthalmology
Characteristics of babies referred to a tertiary eye hospital of Bangladesh for retinopathy of prematurity screening and management, a database analysis
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Retinopathy of prematurity
Treatment options

How to Cite

Niyonzima JC, Nahar N, Chowdhury M, Kumar SD, Rahman M. (2023). Characteristics of babies referred to a tertiary eye hospital of Bangladesh for retinopathy of prematurity screening and management, a database analysis. The Journal of Ophthalmology of Eastern, Central and Southern Africa, 15(01). Retrieved from


Background: IspahaniIslamia Eye Institute and Hospital (IIEIH) is a not for profit hospital and a leading Retinopathy
of Prematurity (ROP) screening center in Bangladesh.

Objective: The study had an aim to analyze the characteristics of referred babies and identify possible bottlenecks
in the referral system.

Methods: Electronic records of babies referred to IIEIH for a period of three years (2016-2018) were analyzed
retrospectively. All the babies registered in the electronic file were screened by any of the three consultants with
a keen interest in ROP. Variables of interest were ROP stage, gestational age, birth weight, time to screening, referring
institution and treatment modalities (laser, Anti-VEGF, retina surgery or combination). Data was exported
to SPSS version 23 for Mac for descriptive and correlation analysis. A P-value of less than 0.05 was considered
statistically significant.

Results: Eight hundred and eighty seven babies with ROP stage 1 or above were registered over the 3 years
period, a large majority were referred mostly by neighbouring private institutions (75%), 60% of babies were
moderate pre-terms according to WHO classification, the mean birth weight was 1563±397.1 grams. ROP stage
2 was dominant (37%) and 61% of any stage ROP babies had at least one treatment modality. There was an obvious
delay in screening since only 55% of babies were screened within a period of less than 8 weeks. The younger
the gestational age and the lower the birth weight, the higher the risk of presenting with ROP with advanced
stage. (P-value<0.001).

Conclusions: The majority of babies with ROP came from private institutions and more than half of them needed
at least one treatment modality. The delay in screening was a key bottleneck and needs to be addressed. We
recommend more NICUS and more ROP services in public hospitals

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