COECSA, Journal, Ophthalmology
Bilateral eyelid Kaposi’s sarcoma: a case report
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Keywords

Eyelid
Kaposi’s sarcoma
Human Herpes Virus type 8
Human Immunodeficiency Virus
Chemotherapy
Highly Active Antiviral Therapy

Categories

How to Cite

Saiko M, Agrippa FM, Rudo MM. (2023). Bilateral eyelid Kaposi’s sarcoma: a case report. The Journal of Ophthalmology of Eastern, Central and Southern Africa, 15(01). Retrieved from https://joecsa.coecsa.org/index.php/joecsa/article/view/293

Abstract

Kaposi’s Sarcoma (KS) is a generalized angio-sarcoma caused by the Human Herpes Virus type 8 (HHV-8).
Infection by the Human Immunodeficiency Virus (HIV) has been shown to predispose to the development of
KS. The commonest location of KS lesions include the skin of the lower limbs, hard palate and gastrointestinal
system, lymph nodes and lungs. The occurrence of KS on the eye is considered rare. We report a case of a 45 year
old HIV positive female patient who presented with bilateral eyelid KS as the first manifestation of systemic KS.
Excisional biopsies were done on both eyelids. The histology showed fascicles of spindle cells and extravasation
of red blood cells. A histological diagnosis of bilateral eyelid KS was made.

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References

Millet A, Singh S, Gittens-Backus G, Dang KA,

Shokrani B. An unusual case of invasive Kaposi’s

sarcoma with primary effusion lymphoma in an

HIV positive patient: case report and literature

review. Case Rep Oncol Med. 2015; 2015:

Teixeira AI, Neno M, Badura R, Borges-Costa

J, Filipe PL. Kaposi sarcoma of the eyelid as an

initial manifestation of AIDS. Dermatol Online J.

; 22(7): 3030/qt2jw6t7cs.

Restrepo CS, Martinez S, Lemos JA, Carrillo JA,

Lemos DF, Ojeda P, et al. Imaging manifestations

of Kaposi sarcoma. Radiographics. 2006; 26(4):

-85.

Pantanowitz L, Dezube BJ. Kaposi’s sarcoma in

unusual locations. BMC Cancer. 2008; 8: 190.

Mangombe S. Eyelid Kaposi’s sarcoma. SA J

Ophthalmol. 2017; 12(3): 13-15.

Schneider JW, Dittmer DP. Diagnosis and

treatment of Kaposi sarcoma. Am J Clin

Dermatol. 2017; 18(4): 529-539.

Crum-Cianflone NF, Hullsiek KH, Ganesan A,

Weintrob A, Okulicz JF, Agan BK. Is Kaposi’s

sarcoma occurring at higher CD4 cell counts over

the course of the HIV epidemic? AIDS. 2010;

(18): 2881-83.

Curtiss P, Strazzulla LC, Friedman-Kien AE.

An update on Kaposi’s sarcoma: Epidemiology,

pathogenesis and treatment. Dermatol Ther

(Heidelb). 2016; 6(4): 465-470.

Jacqueline Freudenthal et al. Ophthalmologic

manifestations of Kaposi’s sarcoma treatment and

management, https://emedicine.medscape.com/

article/1197815-treatment#d8, Medscape, 2019.

Dugel PU, Gill PS, Frangieh GT, Rao NA.

Treatment of ocular adnexal Kaposi’s sarcoma

in acquired immune deficiency syndrome.

Ophthalmology. 1992; 99(7):1127-32.

Kalinske M, Leone CR Jr. Kaposi’s sarcoma

involving eyelid and conjunctiva. Ann

Ophthalmol. 1982; 14:497–499.

Dammacco, R., L. Lapenna, et al. Solitary eyelid

Kaposi sarcoma in an HIV-negative patient.

Cornea. 2006; 25(4): 490-492.

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