Abstract
Malignant melanoma of the conjunctiva is a relatively infrequent neoplasm that can be associated with
significant morbidity and cause diagnostic difficulty to both the ophthalmologist and pathologist. We herein
describe a case of malignant conjunctival melanoma which clinically simulated scleromalcia perforance
causing sclerouveal staphyloma or huge conjunctival cyst. Being rare but potentially lethal tumour,
conjunctival melanoma should be included in the differential diagnosis of slowly growing conjunctival
masses or sclerouveal staphylomas for early detection and management.
References
Seregard S. Conjunctival melanoma. Surv
Ophthalmol. 1998; 42: 321-350.
Jakobiec FA. Conjunctival melanoma. Arch
Ophthalmol. 1980; 98: 1378-1384.
Yu GP, Hu DN, McCormick S, et al. Conjunctival
melanoma: is it increasing in the United States?
Am J Ophthalmol. 2003; 135:800- 806.
Tuomaala S, Kivela T. Conjunctival melanoma:
is it increasing in the United States? Am J
Ophthalmol. 2003; 136:1189-1190.
Folberg R. Melanocytic lesions of the conjunctiva,
in Spencer WH (ed): Ophthalmic Pathology: An
Atlas and Textbook (ed. 4). Philadelphia, PA, WB
Saunders Co. 1996, pp 125-155.
Folberg R, McLean IW, Zimmerman LE.
Malignant melanoma of the conjunctiva. Hum
Pathol. 1985; 16:136-143.
Paridaens AD, Minassian DC, McCartney AC,
et al. Prognostic factors in primary malignant
melanoma of the conjunctiva: A clinicopathological
study of 256 cases. Br J Ophthalmol.
; 78:252-259.
Folberg R, Jakobiec FA, Bernardino VB, et
al. Benign conjunctival melanocytic lesions:
clinicopathologic features. Ophthalmology. 1989;
:436-461.
Shields JA, Shields CL, dePotter P. Surgical
management of conjunctival tumours. The 1994
Lynn B, McMahan Lecture. Arch Ophthalmol.
; 115: 808-815.
Tatla T, Hungerford J, Plowman N, et al.
Conjunctival melanoma: The role of conservative
surgery and radiotherapy in regional metastatic
disease. Laryngoscope. 2005; 115: 817-822.