COECSA, Journal, Ophthalmology
Prevalence of keratoconus in patients with allergic conjunctivitis attending Kenyatta National Hospital eye clinic
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Allergic conjunctivitis
Kenyatta National Hospital


How to Cite

Mugho SN, Ilako D, Nyenze EM. (2023). Prevalence of keratoconus in patients with allergic conjunctivitis attending Kenyatta National Hospital eye clinic. The Journal of Ophthalmology of Eastern, Central and Southern Africa, 15(01). Retrieved from


Objective: To determine the prevalence of keratoconus among patients with allergic conjunctivitis aged
between 8 and 30 years, attending Kenyatta National Hospital eye clinic.

A cross sectional study of patients on follow up for allergic conjunctivitis. They were examined on the
slit lamp, clinical signs of keratoconus were elicited, and then keratometry and corneal topography was done on
each of them. The social demographic and clinical data was captured in a questionnaire. Descriptive analysis of
the data was done to determine means, frequencies and proportions of the various variables. The relationship
between the demographic characteristics of the patients, the duration and severity of allergic conjunctivitis,
with keratoconus was assessed.

Two hundred and forty six eyes of 123 patients were examined. Keratoconus prevalence was found to
be 10.6% by clinical diagnosis, 14.6% by keratometry and 30.9% by topography. Majority of those diagnosed
with keratoconus were aged 10 to 14 years (42.1%). The male: female ratio of those with keratoconus was 1.9:1,
and among them 34.2% had moderate allergic conjunctivitis, and 42.1% had severe allergic conjunctivitis, which
was statistically significant. Patients with allergy symptoms for more than 10 years formed the largest proportion
of those with keratoconus (42.1%).

Conclusion: The prevalence of keratoconus in patients with allergic conjunctivitis was found to be high and
the majority were male. Corneal topography diagnosed more patients with keratoconus, and therefore is highly
recommended as part of the follow up investigations for all patients with allergic conjunctivitis. This will ensure
early detection and management of the condition.

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Gordon-Shaag A, Millodot M, Shnear E. The

epidemiogy and etiology of keratoconus. Int J

Keratoconus Ectatic Dis. 2012; 1(1):7–15.

What Causes Keratoconus| KC theories | Genetic/

Environmental [Internet]. NKCF. [cited 2015 Mar

. Available from:

Nielsen K, Hjortdal J, Aagaard Nohr E, Ehlers N.

Incidence and prevalence of keratoconus in Denmark.

Acta Ophthalmol Scand. 2007: 85(8):890–892.

Cozma I, Atherley C, James NJ. Influence of ethnic

origin on the incidence of keratoconus and associated

atopic disease in Asian and white patients. Eye.


Nowak DM, Gajecka M. Genetics of keratoconus.

Middle East Afr J Ophthalmol [Internet]. 2011:18(1).

Available from:

Bawazeer A, Hodge W, Lorimer B. Atopy and

keratoconus: a multivariate analysis. Br J Ophthalmol.

; 84(8):834 - 836.

Lapid-Gortzak R, Rosen S, Weitzman S, Lifshitz T.

Videokeratography findings in children with vernal

keratoconjunctivitis versus those of healthy children.

Ophthalmology. 2002;109(11):2018–23.

Totan Y, Hepşen I, Çekiç O, Gündüz A, Aydın E.

Incidence of keratoconus in subjects with vernal

keratoconjunctivitis. Ophthalmology. 2001;


Shoja M, Besharati M. Evaluation of keratoconus

by videokeratography in subjects with vernal

keratoconjunctivitis (VKC). J Res Med Sci.


Wade P, Iwuora A, Lopez L, Muhammad M. Allergic

conjunctivitis at Sheikh Zayed Regional Eye Care Center,

Gambia. J Ophthalmic Vis Res. 2012;7(1):24–28.

De Smedt S, Nkurikiye J, Fonteyne Y, Tuft S,

Gilbert C, Kestelyn P. Vernal keratoconjunctivitis

in school children in Rwanda. Ophthalmology.


Waweru F , Bhaiji M. Vernal keratoconjunctivitis as

seen at Kenyatta National Hospital. MMed Thesis;

University of Nairobi. 1991.

Dantas P, Alves M, Nishiwaki-Dantas M.

Topographic corneal changes in patients with

vernal keratoconjunctivitis. Arq Bras Oftalmol.


American Academy. External disease and cornea.

American Academy of Ophthalmology;

Bore M, Ilako D. Clinical evaluation criteria of ocular

allergy by ophthalmologists in Kenya and suggested

grading sysytems. J Ophthalmol East Cent South Afr.


Thengil D. Association between keratoconus and

vernal keratoconjunctivitis/Allergic conjuctivitis in

Zambia. 2014;

John AK, Asimellis G. Revisiting keratoconus

diagnosis and progression classification based on

evaluation of corneal asymmetry indices, derived

from Scheimpflug imaging in keratoconic and suspect

cases. Clin Ophthalmol Auckl NZ. 2013;7:1539–48.

Millodot M, Shneor E, Albou S, Atlani E, Gordon-

Shaag A. Prevalence and associated factors of

keratoconus in Jerusalem: a cross-sectional study.

Ophthalmic Epidemiol. 2011;18(2):91–97.

Ertan A, Muftuoglu O. Keratoconus clinical findings

according to different age and gender groups. Cornea.


Batool J, Henia L, Doyle SR. Asymmetric keratoconus

attributed to eye rubbing. Cornea.[Internet].

LWW. [cited 2014 Nov 26]. Available from: http://




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