COECSA, Journal, Ophthalmology
Ocular flora in newborns of mothers with prolonged labour at the university Teaching Hospital in Lusaka, Zambia



How to Cite

D, K. ., M, K. ., S, M., & L, K. (2020). Ocular flora in newborns of mothers with prolonged labour at the university Teaching Hospital in Lusaka, Zambia. The Journal of Ophthalmology of Eastern, Central and Southern Africa, 16(1). Retrieved from


Objective: To compare the spectrum and quantity of ocular florae in neonates of mothers with Prolonged
Labour (PL) and those of mothers with Normal Labour (NL) delivered at the University Teaching Hospital
(UTH) in Lusaka.
Design: Prospective cohort study.
Setting: University Teaching Hospital, Department of Obstetrics and Gynaecology (labour ward).
Subjects: One hundred and thirty two mother baby pairs.
Results: One hundred and thirty two subjects were enrolled and analysed in equal arms of 66 for PL and NL.
Positive conjunctiva culture results were 28.8% in neonates of mothers with PL and 21.2% in those of mothers
with NL (p-value 0.315). Neonates of mothers with PL had positive culture results with a relative risk of 1.50
(0.68-3.33). A higher colony count was demonstrated in neonates of mothers with PL though not statistically
significant (p-value 0.415). The most frequently isolated organism in NL was Coagulase Negative Staphylococcus
(CNS) where as in PL it was E.coli and Strep viridans (co-existing).
Conclusion: Neonates of mothers with PL had a higher incidence of positive cultures than those of mothers
with NL. This difference was however not clinically significant. Mothers with PL were on systemic antibiotics
which may have influenced the conjunctival culture result and overall colony counts.



Mundia DG, Masinde MS, Ilako DR. Published

MMed dissertation. Risk of developing neonatal

conjunctivitis in newborn of mothers with prolonged

labour. East Afr J Opthal. 2008; 14:5-12.

Theresa, KL, Madhavan, HN. Microbiological procedures

for diagnosis of ocular infections. L&T Microbiology

Research Centre Vision Research foundation.

Eder, M, Farina, N, Sanabria, R, Ta, C, Koss, M,

Samudio, M, et al. Normal ocular flora in newborns

delivered at two hospital centers in Paraguay &

Argentina. Graefe’s Archive Clinical Exper. Ophthal.

; 243(11): 1098-1107.

Gichuhi, S, Bosire, R, Mbori-Gancha, D, Gichuhi, C,

Wamwala, D, Maleche-Obimbo, E. et al. Risk factors for

neonatal conjunctivitis in babies of mothers with

HIV-1 infected mothers. Ophthalmic Epidemiology. 2009;

: 337-345.

Vaughan, A. General Ophthalmology. Lange 1980;

th edition: 331

Isenberg, S, Apt, L, Yoshimori, R, McCarty, J,

Alvarez, S. Source of the conjunctival bacterial flora

at birth and implications for ophthalmia neonatorum

prophylaxis. Am J Ophthalmol. 1988;106(4):458-462.

Jafferji, S, Ilako, D, Kollmann, M, Kariuki, M. Antibiotic

sensitivity pattern of staphylococcus aureus.

East Afr J Ophthal. 2008; 14: 29-37.

Zoga, O, Njuguna, M, Gichuhi, S, Trivedy, J. M.Med

dissertation. Effect of combining conjunctiva fornix

irrigation with lid scrubs as a method of pre-operative

preparation in cataract surgery-A randomized

controlled trial of the effect of 5% Povidone iodine on

the normal flora of the ocular adnexa. East Afr J Ophthal.


Prentice, M, Hutchinson, G, Taylor-Robinson, D.

A microbiological study of neonatal conjunctivae and

conjunctivitis. Br J Ophthal. 1977;61:601-607.


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